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This activity will review the latest PK recommendations for Factor VIII and IX replacement and how to use and interpret PK parameters to assess treatment plans.

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Beta-lactam Allergies: Facts and Fears

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To Participate

To participate in this continuing education activity:

  1. Review the activity description and objectives.
  2. View the activity.
  3. Complete the online post-test and activity evaluation.
A product of the Society of Infectious Diseases Pharmacists Education Center (SIDPEC) 

 View more SIDPEC Activities

Note: If you attended the live CE activity titled "Beta-lactam Allergies: Facts and Fears" at the ASM Microbe Meeting on June 1, 2017 in New Orleans, Louisiana AND received CE credit (i.e. a pharmacist CE statement of credit with ACPE UAN 0072-9999-17-015-L01-P), you are ineligible to also receive credit for this home-study on-demand web activity.

Activity Description

The issue of a patient’s allergy status to needed antibiotics is always a dilemma. The patient’s true risk of hypersensitivity or cross reactivity to various agents is an important consideration in antibiotic selection. This educational activity will address some of the risk factors for cross reactivity to penicillin and beta lactam agents. Selected cases will be reviewed and discussed. Penicillin skin testing and the usefulness of testing will be reviewed. A discussion of some legal cases involving allergy medical negligence and their outcomes will also be presented.

This is a featured CE activity on the Society of Infectious Diseases Pharmacists Education Center (SIDPEC) website. SIDPEC is the educational hub of the Society of Infectious Diseases Pharmacists (SIDP). The SIDPEC portal provides educational activities on infectious disease pharmacotherapy for clinical pharmacists, health‐systems pharmacists, community pharmacists, and other allied‐health disciplines.

Learning Objectives

At the conclusion of this activity, participants should be able to:

  • Identify risk of cross-reactivity among beta-lactams
  • Discuss the utility of penicillin-skin testing for patients labeled as penicillin allergic
  • Review medical negligence cases involving beta-lactam use in penicillin allergic patients


Meghan Jeffres, PharmD
Assistant Professor, Department of Clinical Pharmacy
University of Colorado, Skaggs School of Pharmacy and Pharmaceutical Sciences
Aurora, Colorado


No commercial funding was received for this activity.

CE Accreditation

Release Date: 6-1-2017
Expiration Date: 6-15-2019


APCE This CE activity is jointly provided by West Virginia University School of Pharmacy (WVUSoP), ProCE, Inc. and SIDP. West Virginia University School of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. ACPE Universal Activity Number 0072-9999-17-015-H01-P has been assigned to this knowledge-based home-study CE activity (initial release date 6-1-2017). This CE activity is approved for 0.75 contact hour (0.075 CEU) in states that recognize ACPE providers. This CE activity is provided at no cost to participants. Completion of an evaluation and post-test with a score of 70% or higher is required to receive CE credit. CE credit will be uploaded to NABP/CPE Monitor. No partial credit will be given.


It is the policy of ProCE, Inc. to ensure balance, independence, objectivity and scientific rigor in all of its continuing education activities. Faculty must disclose to participants any significant financial interest or affiliation with companies that manufacture or market products discussed in this activity. Dr. Jeffres has no relevant commercial and/or financial relationships to disclose.

Please note: The information and views presented in this activity are those of the faculty through clinical practice and knowledge of the professional literature. Portions of this activity may include the use of drugs and/or devices for unlabeled indications, which should be considered experimental. Participants are advised to consult manufacturer product information and the professional literature, and use professional judgment in applying the presented information in patient-care activities.

The material presented in this CE activity does not reflect the views of ProCE, Inc. or the commercial sponsor. These materials may discuss uses and dosages for therapeutic products, processes, procedures and inferred diagnoses that have not been approved by the United States Food and Drug Administration. A qualified health care professional should be consulted before using any therapeutic product discussed. All readers and continuing education participants should verify all information and data before treating patients or employing any therapies described in this continuing education activity.

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