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True Penicillin Allergy in the Era of Antimicrobial Resistance

Activity Downloads

To Participate

To participate in this continuing education activity:

  1. Review the activity description and objectives.
  2. View the activity.
  3. Complete the online post-test and activity evaluation.

Note: If you attended the live CE activity AND received CE credit (i.e. a pharmacist CE statement of credit with ACPE UAN 0221-9999-19-285-L01-P), you are NOT allowed to also receive credit for this home-study on-demand web activity.


A product of the Society of Infectious Diseases Pharmacists Education Center (SIDPEC) 

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Activity Description

Penicillin, a beta-lactam antibiotic, is the most commonly reported drug allergy. In the United States, approximately 32 million people have a documented penicillin allergy. Yet as few as 10% are truly allergic. Consequences of inappropriate allergy documentation range from treatment failures to the potential development of antimicrobial resistance. Fortunately, options to re-evaluate penicillin allergies and institutional-based programs have recently gathered more attention. This activity will provide actionable information to address incorrect or outdated beta-lactam allergy reports and to provide pharmacists, nurses, and other key stakeholders opportunities to impact care and antimicrobial stewardship best practices.

Learning Objectives

The target audience for this activity includes pharmacists and nurses. At the completion of this activity, the participant will be able to:

  • Compare and contrast the different types of drug hypersensitivity reactions.
  • Describe the risks and complications associated with inaccurate penicillin allergy documentation.
  • Outline strategies to implement penicillin allergy reconciliation and testing.


Mary Staicu, PharmD, BCIDP
Infectious Diseases Clinical Pharmacy Specialist
Rochester General Hospital, Department of Pharmacy
Rochester, New York

CE Accreditation

Release Date: 9-25-2019
Expiration Date: 10-23-2020


This activity is jointly provided by ProCE, Inc. and the Society of Infectious Diseases Pharmacists. ProCE, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. ACPE Universal Activity Number 0221-9999-19-285-H01-P has been assigned to this home study knowledge-based activity. This activity is approved for 1.0 contact hours (0.1 CEU) in states that recognize ACPE providers. The activity is provided at no cost to participants. Participants must complete the online post-test and activity evaluation to receive pharmacy CE credit. No partial credit will be given. Statements of completion will be issued online at, and proof of completion will be posted in NABP CPE Monitor profiles.


This CE activity is jointly provided by ProCE, Inc. and Wild Iris Medical Education, Inc. This activity provides 1.0 contact hour of nurse CE credit.

Wild Iris Medical Education, Inc. is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.


It is the policy of ProCE, Inc. to ensure balance, independence, objectivity and scientific rigor in all of its continuing education activities. Faculty must disclose to participants any significant financial interest or affiliation with companies that manufacture or market products discussed during their presentation. Dr. Staicu is an advisory board member for ALK. Potential conflict of interest was resolved with an outside peer review.


This activity is supported by an educational grant from ALK.


The material presented in this CE activity does not reflect the views of ProCE, Inc. or the commercial sponsor. These materials may discuss uses and dosages for therapeutic products, processes, procedures and inferred diagnoses that have not been approved by the United States Food and Drug Administration. A qualified health care professional should be consulted before using any therapeutic product discussed. All readers and continuing education participants should verify all information and data before treating patients or employing any therapies described in this continuing education activity.